The Thousand-Dollar Alignment

In this episode of A Coffee with CompBio, Lorena and Alex share the twists and turns of realizing their methylation data wasn’t what it seemed. From puzzlingly low mapping rates to unexpected cloud costs caused by unoptimized compute jobs—thankfully caught just in time thanks to cost alarms—they highlight how essential clear communication and bioinformatics-aware experimental design are to any successful project.

In our new segments, Quick Sips and Brewing Up for Answers, we talk about PIXI for managing software environments and dig into the ever-present challenge of staying organized…