About this podcast
Welcome to Biotech Bulls & Breakthroughs! This brand new podcast from BioPharmCatalyst explores the dynamic world of biotech investing alongside long-time biotech trader Sheff from Sheff Station. Each month, we will be discussing current events in the biotech industry and how these events impact investors, as well as a discussion of upcoming catalysts in the biotech space.
Episodes
The newest 20 of 23 episodes
- Biotech Stocks to Watch: FDA Shakeups, ESMO Data & Late 2026 Biotech Catalysts Sheff Is Watching · 46 min · Season 2 Episode 9The FDA is in flux, ESMO is approaching, and a series of clinical and regulatory catalysts could put biotech stocks in focus. John Gagliano and Sheff Sheffield mark their 20th…
- Biotech Stocks to Watch: The September – December Catalysts Sheff Is Watching · 52 min · Season 2 Episode 8In this episode, John Gagliano and Sheff Sheffield discuss the biggest biotech catalysts heading into the final months of 2026. They examine continued big-pharma acquisition…
- Lithium, brain imaging, & the future of Alzheimer’s treatment with Alzamend CEO Stephan Jackman ALZN · 26 min · Season 2 Episode 7In this episode features John Gagliano in conversation with Stephan Jackman, CEO and director of Alzamend, about the company’s mission, “Making Alzheimer’s just a memory,” and…
- Biotech Stocks Catalyst to Watch Fall 2026: The Surprising Impact of FDA Adcom Meetings · 44 min · Season 2 Episode 6In this episode, John Gagliano and Sheff Sheffield unlock hidden strategies behind biotech success, from FDA decision dynamics to the most promising upcoming catalysts; they…
- Middle to 3Q 2026 Biotech Catalyst: FDA Policy Shifts and Their Impact on Biotech Stocks · 1 h 0 min · Season 2 Episode 5In this episode, John Gagliano and Sheff Sheffield discuss recent developments in biotech, including FDA policy shifts, key catalysts for upcoming biotech stocks, and market…
- The Hidden Power of One Pivotal Trial That Changed FDA’s Game | Biotech Bulls & Breakthroughs · 56 min · Season 2 Episode 4In this episode, John Gagliano and Sheff Sheffield unpack the game-changing FDA decision that could add millions to Outlook Therapeutics’ valuation overnight. You'll discover how…
- Biotech Investing: Biotech Mid 2026 Catalysts To Watch · 1 h 5 min · Season 2 Episode 6In this episode, as the biotech earnings season continues, John Gagliano and Sheff Sheffield explore the resilience of the biotech market, the impact of FDA policies, and the…
- The Future of Biomanufacturing | Michael Heltzen, eXoZymes · 32 min · Season 2 Episode 5In this episode of Biotech Bulls & Breakthroughs, John sits down with Michael Heltzen, CEO of exoZymes, to discuss the revolutionary move toward cell-free biomanufacturing…
- Biotech Investing: FDA One Pivotal Trial and 2Q Outlook | Biotech Bulls & Breakthroughs · 38 min · Season 2 Episode 4In this episode, as the biotech earnings season continues, John Gagliano and Sheff Sheffield dive deep into the new FDA one pivotal trial as an alternative to the regulatory…
- Tackling Rare Genetic Diseases with Diagonal Therapeutics · 20 min · Season 2 Episode 3In this episode, John Gagliano speaks with Eric Duhaime, Senior VP of Finance and Corporate Development at Diagonal Therapeutics, about the innovative approaches the company is…
- Talking Biotech: Biotech Stocks to Watch, Hedge Funds & More · 1 h 15 min · Season 2 Episode 2In this episode, as the biotech earnings season continues, John Gagliano and Sheff Sheffield explore the importance of cash burn in biotech, the role of hedge funds, and the many…
- Navigating the Future of Biotech: Insights from the JP Morgan Healthcare Conference 2026 · 50 min · Season 2 Episode 1In this episode, as the biotech landscape continues to evolve, the recent JP Morgan Healthcare Conference 2026 has set the stage for an exciting year ahead. John Gagliano and…
- 2025 Biotech Recap & Set Up For 2026 · 48 min · Season 1 Episode 11In this episode, John Gagliano and Chef Sheffield review the biotech landscape of 2025, discussing key trends, FDA clarity, and the impact of CRLs on investor confidence. They…
- Understanding Catalysts in Biotech Trading · 50 min · Season 1 Episode 10In this episode, John Gagliano and Sheff Sheffield discuss the current state of the biotech market as they approach the end of the year. They reflect on recent trading successes…
- Innovations in Biotech: A Deep Dive with MoMA Therapeutics · 30 min · Season 1 Episode 9In this episode, John Gagliano speaks with Neil Lineberry, VP of Corporate Development at MoMA Therapeutics, about the innovative approaches the company is taking in drug…
- Ep. 5: Biotech Trends and Insights: Rare Diseases, Patent Expirations, ESMO25 and Sheff's Watchlist | Biotech Bulls & Breakthroughs Podcast · 51 min · Season 1 Episode 8In this episode of Biotech Bulls and Breakthroughs, John Gagliano and Christopher Sheffield discuss the current state of the biotech market, focusing on trends, upcoming…
- Ep. 4: Navigating the Biotech Landscape | Biotech Bulls & Breakthroughs Podcast · 1 h 5 min · Season 1 Episode 7In this episode, John Gagliano and Sheff discuss the latest trends in the biotech market, focusing on key companies, earnings season insights, and upcoming catalysts. They…
- Biopharma Industry: Insights from BioSpace Senior Editor Annalee Armstrong · 30 min · Season 1 Episode 6In this episode of Biotech Bulls and Breakthroughs, host John Gagliano speaks with Annalee Armstrong, Senior Editor at BioSpace, about the current state of the biopharma…
- Ep. 3: Stock Picking and Catalyst Research | Biotech Bulls & Breakthroughs Podcast · 1 h 1 min · Season 1 Episode 5In this episode, John Gagliano and Sheff discuss current trends in the biotech market, focusing on investment strategies, the importance of catalyst dates, and stock evaluation…
- Unlocking Biotech: Insights from The Biotech Investor (Waseem Laroussi) · 30 min · Season 1 Episode 4In this episode, biotech content creator The Biotech Investor (Wassim Laroussi) shares his unique journey into biotech investing, discussing his background, strategies for…
