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Intellectually Curious

Intellectually Curious

How Claude Helped Map a Vault Particle

· 7 min

Show notes

In 1986, two researchers spotted a tiny structure whose curved ribs reminded them of a cathedral ceiling. They called it a vault. Forty years later, scientists are still working out what these tiny barrels do in our cells. We follow a team at Anthropic that used Claude to search for relatives of these hollow protein shells. One promising lead came from a virus that infects bacteria. The researchers grew its protein in E. coli and used an electron microscope to see how 96 copies fit together ...

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