BioTalk Unzipped
by Gregory Austin
Latest episode
Why Finding the Right Drug Dose Is So Difficult | Dr. Ewoud-Jan van…
Why Finding the Right Drug Dose Is So Difficult | Dr. Ewoud-Jan van…
About this podcast
BioTalk Unzipped, hosted by Gregory Austin and Dr. Chad Briscoe, unzips the stories behind medical progress through candid, intelligent, and often entertaining conversations with leaders across biotechnology, pharmaceuticals, medical technology, clinical research, bioanalysis, and drug development.
Each episode explores the science, strategy, setbacks, breakthroughs, and human stories shaping the future of medicine. From first-in-human trials and biomarkers to oncology, rare disease, AI, regulatory strategy, and emerging therapeutic technologies, BioTalk Unzipped makes complex life science topics engaging, accessible, and relevant.
The show feels like the conversation you would want to overhear after a great scientific conference: thoughtful, unscripted, curious, and grounded in real-world experience. We bring listeners inside the decisions, discoveries, and personal journeys behind the therapies and technologies that may one day reduce suffering and improve lives.
Episodes
The newest 20 of 48 episodes
- Why Finding the Right Drug Dose Is So Difficult | Dr. Ewoud-Jan van Hoogdalem · 54 min · Season 1 Episode 48A drug shows promise in a small patient study. How much does that tell you about the dose you should test next? Gregory Austin and Dr. Chad Briscoe explore that question with Dr…
- Is AI Changing Scientists? The Future of Pharma with Dr. Rob Dodge · 36 min · Season 1 Episode 47Rob Dodge says AI has made him an expert Python programmer, even though he never took a class in it. But does having new capabilities change what it means to be a scientist? Dr…
- Do Clinical Trials Take Too Much Blood? Patient-Centric Sampling with Joleen White · 48 min · Season 1 Episode 46Clinical trials often collect far more blood than an assay actually needs. Dr. Joleen White asks a more disciplined question: What information is required to make a sound…
- Why Gene Therapy Is Still So Hard to Manufacture at Scale | Phillip Ramsey · 11 min · Season 1 Episode 45Why is gene therapy still so difficult to manufacture at scale after decades of progress? Phillip Ramsey, Chief Technical Officer at Sangamo Therapeutics, joins BioTalk Unzipped…
- Her Daughter’s Brain Tumor Turned Her Into a Biotech Founder | Tracy Ryan · 1 h 4 min · Season 1 Episode 44A mother’s search for answers to her daughter’s relentless brain tumor led her into natural killer cell biology, cancer immunotherapy, and biotech entrepreneurship. Sponsored by…
- The Future of Oncology Drug Development | Dr. Lakshmi Amaravadi · 30 min · Season 1 Episode 43Oncology drug development is becoming more complex, and bioanalysis can no longer be treated as simple drug measurement. Sponsored by Leucentra, https://leucentra.com/ Inspired…
- Active Machine Learning for Drug Discovery & Nanomedicine with Dr. Daniel Reker · 51 min · Season 1 Episode 42Can artificial intelligence help make cancer therapies safer, more targeted, and more effective? In this episode of BioTalk Unzipped, Gregory Austin sits down with Dr. Daniel…
- Why Haven’t We Cured Cancer Yet? | Dr. Bob Liu Explains · 1 h 0 min · Season 1 Episode 41Why haven’t we cured cancer yet? A Genentech scientist explains the real reason. In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Bob…
- The Intersection of Biotech, Patent Law, and AI with Dr. Kate Neville, IP Attorney · 53 min · Season 1 Episode 40Recorded October 31, 2025 In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Kate Neville, immunologist turned seasoned biotech patent…
- Long-acting Cell-Based Gene Therapy, Fabry Disease and Beyond with Glafabra CEO, Dr. Chris Hopkins · 49 min · Season 1 Episode 39In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe sit down with Glafabra CEO: Dr. Chris Hopkins, geneticist, biochemist, and biotech entrepreneur, to…
- Fail Fast, Learn Faster: Drug Development in Rare Disease with Dr. Binodh DeSilva · 31 min · Season 1 Episode 38In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Binodh DeSilva, Senior Vice President of Bioanalysis at Ultragenyx Pharmaceutical, to…
- Unlocking Antibody Development with AI with Dr. Pin-Kuang Lai · 18 min · Season 1 Episode 37In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe interview Asst. Professor Pin-Kuang Lai from Stevens Institute of Technology about his keynote…
- The Science and Hope of Brain Cancer with Dr. Robert Thorne, Denali Therapeutics · 22 min · Season 1 Episode 36In this powerful episode (#35) of BioTalk Unzipped, recorded live at the AAPS NBC conference in Boston, Gregory Austin engages in a deep conversation with a leading…
- Inside AAPS NBC with AAPS President Dr. Russ Weiner · 28 min · Season 1 Episode 35In this special episode (#34) of BioTalk Unzipped, recorded live at the AAPS NBC conference in Boston, Gregory Austin and Dr. Chad Briscoe sit down with AAPS President Dr. Russ…
- Building Successful Life Science Companies with Katrina Rogers · 60 min · Season 1 Episode 34In this powerful episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Katrina Rogers, a 25-year life sciences veteran, biotech equity advocate, and…
- Navigating Challenges in Drug Discovery with Dr. Alfred Botchway · 52 min · Season 1 Episode 33In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Alfred Botchway, CEO of Attentive Science, to discuss his journey in biomedical science…
- 2024 Year In Review: BioTalk Unzipped · 42 min · Season 1 Episode 32In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe reflect on their journey over the past year, discussing key themes and insights gained from their…
- Women in Pharmaceutical Sciences and their Allies with Dr. Ines Santos and Dr. Julie Sable · 1 h 11 min · Season 1 Episode 31In this episode of BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe welcome Dr. Ines Santos and Dr. Julia Sable to discuss their experiences and contributions in the…
- Can AI Become Your Doctor? FDA Regulation, Medical Devices & the Future of Healthcare · 1 h 9 min · Season 1 Episode 30Could artificial intelligence become your doctor someday? In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Alex Friedman, a regulatory…
- The Future of Dosing: Pharmacometrics, Oncology & Virtual Trials with Dr. Nathan Teuscher · 32 min · Season 1 Episode 29In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe continue their conversation with Dr. Nathan Teuscher, a clinical pharmacology and pharmacometrics expert…
