Ground Truths
by Eric Topol
Latest episode
Vadim Gladyshev and the Science of Aging
Vadim Gladyshev and the Science of Aging
About this podcast
Facts, data, and analytics about biomedical matters.
erictopol.substack.com
Episodes
The newest 20 of 98 episodes
- Vadim Gladyshev and the Science of Aging · 50 minVadim Gladyshev, PhD, Professor of Medicine at Brigham and Women's Hospital, Harvard Medical School, elected to the National Academy of Science, is a prolific science of aging…
- Michael Lewis: The NIH “Murder Mystery,” DOGE, and Our Government Immune System · 1 h 3 minMichael Lewis is one of the best storytellers of our era. You know and likely have read his books Moneyball, The Big Short, The Blind Side, Flash Boys, Liar’s Poker, and The…
- Marios Georgakis: Why Did Two Major Clinical Trials for Heart Disease Fail? · 1 h 8 minIn recent weeks the results (announced by press release) of 2 major placebo-controlled randomized trials—ZEUS, testing an interleukin-6 (IL-6) blocker vs inflammation, and…
- Two Landmark Studies Challenge Dogma About our Brain Immune Cells and Aging · 44 minThis podcast is meant to complement my recent Ground Truths post Why Our Memory Slips After Age 50 which has all the relevant links to the 2 papers, key graphics, and other…
- Deborah Cohen: The Wellness-Industrial Complex · 59 minDeb Cohen is an award winning investigative journalist and correspondent who trained as a physician and has worked with the BBC and BMJ. She just published BAD INFLUENCE, a book…
- Sarah Urbut: Predicting Your Health Arc · 54 minSarah Urbut is a physician-scientist at Harvard Medical School and the Massachusetts General Research Institute. She and her colleagues published a landmark paper in Nature on…
- Patrick Hsu: How Is AI Catalyzing Life Science? · 58 min“The future of biology is programmable.” To give you a sense of how important this topic is, Patrick Hsu is the first guest we’ve had back to Ground Truths since the podcast…
- Aaron Newman: A Breakthrough Blood Test for Cancer · 48 minThe tumor microenvironment (TME), composed of immune cells, fibroblasts, and endothelial cells, has emerged as critical to pathogenesis, prognosis and treatment for cancer…
- Elisa Port: Discuss THE BREAST ADVICE Book · 1 h 3 min“I may be the expert in cancer, but you are the expert in you.”—Elisa Port, MD Ground Truths is a reader-supported publication. To receive new posts and support my work…
- Helen Pearson: What Constitutes Real Medical Evidence? · 52 minHelen Pearson, PhD, is an award-winning biomedical journalist at Nature, named European Science Journalist of the Year in 2025. She teaches science writing at University College…
- Assessment of the Hantavirus with Prof Donald Milton · 52 minGet full access to Ground Truths at erictopol.substack.com/subscribe
- Joanna Stern: An AI Immersion for 365 Days · 58 minJoanna Stern was the Wall Street Journal technology journalist for 12 years. She’s an Emmy award winner for her documentary E-Ternal, and recently started her own company New…
- Roxanne Khamsi: We Are All Genetic Mosaics · 52 min“You are a slightly different genetic version of yourself today from yesterday, and will be different yet again tomorrow.”—Roxanne Khamsi “Each neuron really is a beautiful and…
- Sebastian Mallaby: The Infinity Machine · 54 minThis is one of my favorite books over recent years. Sebastian Mallaby is the Paul A. Cocker Senior Fellow for International Economics at the Council of Foreign Relations and…
- Trisha Pasricha: How to Get to Poophoria, Making Your Bowel Movements a Joy! · 57 minDr. Trisha Pasricha is a gastroenterologist, Assistant Professor at Harvard Medical School, and the Ask a Doctor columnist for The Washington Post. Her new book gets deep into…
- On the Future of Species · 45 minAdrian is a molecular biologist and co-founder and CEO of Genyro, a synthetic biology company. He has published 2 previous books on life science (Life Without Genes and An…
- A Master Class on Sleep · 57 minYo-El Ju is the Barbara Burton and Reuben Morris Professor of Neurology at Washington University, St. Louis. She got her AB from Harvard and MD from Columbia and actively…
- Robert Wachter & Eric Topol - Discuss a Giant Leap Book · 46 minGet full access to Ground Truths at erictopol.substack.com/subscribe
- Vagus Nerve Stimulation and the Immune System · 1 h 3 minThe vagus nerve, also known as the Great Nerve, connects the brain to all parts of the body, like an internet (Figure below). Every week we’re learning more about its importance…
- A Look Into the Blue Zones · 56 minBack in 2005 Dan Buettner patented Blue Zones. He’s written 9 books, of which 5 were NY Times bestsellers, and has another one in the works. His 2023 Netflix documentary series…







