In Silico Trials, Real Impacts!
by UK CEiRSI | InSilicoUK
Latest episode
Digital Twins & Virtual Patients: Revolutionising Paediatric…
Digital Twins & Virtual Patients: Revolutionising Paediatric…
About this podcast
We’re uniting visionaries to craft a national strategy that fast-tracks virtual clinical trials, propelling the UK to the forefront of healthcare innovation. Join us as we explore how computational modelling is reshaping patient care, boosting the economy, and accelerating medical breakthroughs. Tune in for insights on creating the UK’s optimal ecosystem for in silico evidence in medicine. The future of healthcare is here – be part of the revolution.
Episodes
The newest 20 of 43 episodes
- Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials · 28 min · Season 1 Episode 43Virtual patient data—digital twins, synthetic datasets, and in-silico trials—offers transformative potential for paediatric clinical research by addressing low enrolment and…
- Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery · 22 min · Season 1 Episode 42Revolutionary CFD modelling transforms Fontan surgery planning for single ventricle patients with interrupted IVC. Boston Children’s Hospital researchers developed 3D virtual…
- Future-Proofing the UK Life Sciences Sector · 17 min · Season 1 Episode 41Are you ready for the UK’s life sciences revolution? Discover how AI and in silico technologies are creating dramatic employment growth across health tech sectors. This episode…
- Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard · 33 min · Season 1 Episode 40Are Randomised Controlled Trials (RCTs) truly the gold standard of research? In the latest episode of In Silico Trials, Real Impacts!, we challenge this long-held belief by…
- Simpler or Complex: Rethinking Occam's Razor in Modelling Science · 28 min · Season 1 Episode 39Is simplicity always better? Ockham’s Razor suggests so, but modern science often thrives on complexity. This episode explores how parsimony has shaped scientific progress and…
- Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar · 16 min · Episode 38In this episode, we explore the impact of computer simulations on diabetes care, focusing on the transition from the Medtronic Guardian Sensor 3 to the Guardian 4 sensor within…
- Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning · 17 min · Season 1 Episode 37What is Evidence-Based Medicine Plus (EBM+)? EBM+ expands traditional Evidence-Based Medicine by integrating mechanistic evidence, patient preferences, and real-world data. This…
- What Underpins Model Credibility? Three Philosophical Perspectives · 19 min · Season 1 Episode 36What underpins model credibility? Join us in our next episode as we delve into the complexities of evaluating model quality. Discover how philosophers of science tackle concepts…
- Exploring Digital Twins: The Philosophy Behind Healthcare's Digital Revolution · 20 min · Episode 35Can a virtual copy of reality help us predict the future? Dive into the fascinating world of digital twins - technology that creates living, breathing virtual replicas of real…
- Cracking the Code: Unveiling the Trustworthy World of In-Silico Trials · 25 min · Season 1 Episode 34Are virtual trials the future of medical regulation? We explore how computational models are being validated for regulatory use, examining credibility frameworks based on the…
- Revolutionising Healthcare: The Power of Synthetic Data · 16 min · Season 1 Episode 33Are we prepared to govern synthetic data in healthcare? This episode examines how AI- or simulation-generated medical data offers enhanced privacy and research efficiency whilst…
- How Can We Trust Computational Models in Healthcare? A Framework for In Silico Clinical Trials · 23 min · Season 1 Episode 32In this episode, we explore the innovative realm of in silico clinical trials (ISCTs), which utilize computational models to evaluate medical interventions. We discuss a recent…
- Probability & Patients: The Stochastic Science Behind In Silico Trial Breakthroughs · 14 min · Season 1 Episode 31Discover how cutting-edge Bayesian methods are transforming healthcare innovation by blending virtual patient data with clinical trials. This episode unpacks a groundbreaking…
- How can we properly evaluate the true economic impact of AI in healthcare? · 23 min · Season 1 Episode 30Are economic evaluation standards keeping pace with AI healthcare innovations? This podcast explores the CHEERS-AI guidelines—a specialized framework designed to address the…
- Revolutionising Healthcare: Inside the UK's MHRA Data Strategy · 18 min · Season 1 Episode 29Could computational modeling revolutionize healthcare regulation? Join us as we dissect the MHRA’s ambitious 2024-2027 data strategy, which aims to usher in a fourth industrial…
- Unleashing the Potential of Health Data: Insights from the Sudlow Review · 22 min · Season 1 Episode 28We delve into the Sudlow Review, examining its groundbreaking recommendations for improving the use of health data in the UK. This episode highlights the immense potential of…
- Regulatory Frontiers: UK's Centres of Excellence in Regulatory Science and Innovation · 19 min · Season 1 Episode 27This episode examines the UK’s strategic investment in Centres of Excellence in Regulatory Science and Innovation (CERSI), focusing on two of seven government-funded centres. We…
- Can NHS Secure Data Environments Unlock the Future of UK Life Sciences? · 40 min · Season 1 Episode 26This episode examines the critical intersection of NHS data infrastructure and life sciences innovation through the lens of a recent ABPI report. The assessment, conducted in…
- Virtual You vs Cancer: How Digital Twins Are Revolutionizing Treatment · 23 min · Season 1 Episode 25What if we could predict your unique cancer treatment response before starting therapy? Digital twins - originally developed for aeronautics - are revolutionising oncology care…
- Digital Footprints to Medical Breakthroughs: The Real-World Data Revolution · 19 min · Season 1 Episode 24What if the future of healthcare innovation lies not in controlled trials, but in the digital footprints we leave every day? Real-world data from health records, wearables, and…
