Pharm to Table
by LC Campeau, Dani Schultz
Latest episode
SE5:E5 - Part 2: Protecting Groups? We Need to Talk: Manufacturing…
SE5:E5 - Part 2: Protecting Groups? We Need to Talk: Manufacturing…
About this podcast
A podcast hosted by L.-C. Campeau and Dani Schultz that dives into the stories about the people behind the chemistry and science that happens at #MerckChemistry.
Follow us on X (formerly Twitter) at @PharmToTablePod, @DrLCSquare, @danithechemist
Email us comments and suggestions at [email protected]
Episodes
The newest 20 of 57 episodes
- SE5:E5 - Part 2: Protecting Groups? We Need to Talk: Manufacturing MK-0616 with Enzyme Cascades · 31 min · Season 5 Episode 5Part 1 laid out the strategy. Now, it’s time to make the molecule. Four enzymes, one vessel, and plenty of competing amines. What could possibly go wrong? Dani and LC return with…
- SE5:E4 - Part 1: Protecting Groups? We Need to Talk: Manufacturing MK-0616 with Enzyme Cascades · 30 min · Season 5 Episode 4How do you design a manufacturing process for a molecule as complex as MK-0616? In Part 1 of this Pharm to Table series, Dani and LC join Stephanie Galanie, Director in…
- SE5:E3: A Process Chemist's Romance with Scaling a Macrocyclic Peptide · 35 minLast episode, we watched medicinal chemistry dream up enclitide (MK-0616) — this week we find out what happens when someone actually has to make it. Dani and LC are joined by…
- SE5:E2: The Macrocyclic Mullet · 27 minWhat happens when the textbook SAR playbook stops working? On this episode of Pharm to Table, Rob Garbaccio joins Dani and LC to share the discovery story behind enlicitide…
- SE5:E1 - A Journey of Synthetic Chemistry Innovations at Merck · 41 min · Season 5 Episode 1To kick off Season 5, Dani and LC discuss a recent perspective published in the Journal of Organic Chemistry that highlights innovations in synthetic chemistry which trace their…
- SE4:E8: From Discovery to Process, Part 2: Getting Ugi with it - scaling a 3CL protease inhibitor · 31 minIn Part 2 of our Pharm to Table deep dive on MK‑7845, Dani and LC shift from invention to implementation, welcoming process chemists Nastaran Salehi Marzijarani and Ben Turnbull…
- SE4:E7: From Discovery to Process, Part 1: Building a 3CL Protease Inhibitor Through Smart Fluorine Placement and Design Intuition · 29 min · Season 4 Episode 11In this first installment of our two‑part Pharm to Table special on MK‑7845, Dani and LC sit down with medicinal chemist Valerie Shurtleff to unpack the discovery journey behind…
- SE4:E6 - Mechanism-Driven Innovation in Process Research: Yining Ji Chen’s Road as a Rising Star · 31 minJoin us for a conversation with Yining Ji Chen, recipient of the 2025 ACS Rising Star Award, on how mechanistic insight powers innovation in pharmaceutical process research. We…
- SE4:E5 - Evolution of a Green Chemistry Trailblazer · 37 min · Season 4 Episode 5In this episode, Dani and LC welcome Jeff Moore, recipient of the 2025 ACS Affordable Green Chemistry Award, to discuss his pioneering work in biocatalysis at Merck. The…
- SE4:E4 - MedChem Masters: Molecules, Mentors and Mindsets · 36 min · Season 4 Episode 4In this episode, Dani and LC interview Dr. Shane Krska, recipient of the ACS Arthur C. Cope Award, and Dr. Petr Vachal, recipient of the ACS Earle B. Barnes Award for Leadership…
- S4:E3 - London Calling ... Spirocycles · 34 min · Season 4 Episode 3This month we sit down with Damien Valette, Olivia Boyd and David Petrone to chat about their latest paper in Organic Letters on the desymmetrization of prochiral dienones to…
- S4:E2 - Making Sulfur Smell like Success! · 27 minJoin us on the Pharm to Table podcast for a delightful chat with Ethan Wappes from our South San Francisco site, as we dive into the exciting world of thiophene synthesis! Ethan…
- S4:E1 Chemistry Unplugged: Listener Q&A and Future Insights · 29 minWe're kicking off Season 4 (holy cow!) by having a lively discussion answering listener questions on everything from our favorite Boc deprotection methods to the role of AI in…
- S3:E10 - Look what ADCs made us do · 36 min · Season 3 Episode 12Antibody drug conjugates, or ADCs, are all the rage in the industry right now and chemists play an important role in their development. This month we sat down with Serge Ruccolo…
- S3:E9 - Surfing peptide production by going with the flow · 33 minReady to go with the flow? Then this episode is for you! In this episode, we dive into the exciting world of Continuous-Flow Solid-Phase Peptide Synthesis (CF-SPPS) with special…
- S3:E8 - So you think you want to start a chemistry podcast? · 26 min · Season 3 Episode 8Join Dani and LC as they peel back the layers on podcasting in chemistry. This insightful episode dives into their recently published Organic Letters editorial "Should You Start…
- S3:E7 - Your Rx for a Pharma Job: Insider Secrets (Part 2) · 25 min · Season 3 Episode 8Time for the main course! Our #MerckChemistry hiring experts are dishing out more savory tips to help you get hired in pharma. In this second part, they'll guide you through…
- S3:E6 - Your Rx for a Pharma Job: Insider Secrets (Part 1) · 27 min · Season 3 Episode 6Looking to kickstart your career in the pharmaceutical industry? This episode is a must-listen! We have special guests Jamie McCabe Dunn, Val Shurtleff and our very own Dani…
- S3:E5 - When Robots Work-It-Up! · 35 min · Season 3 Episode 5Alexandra Sun and Harrison Rose join the pod to share their work on a vision-guided automated liquid-liquid extraction (LLE) platform. That's right, before our robot overlords…
- S3:E4 - "Asta La Vista, Baby" - The Aminator · 21 min · Season 3 Episode 4Patrick Fier and Suhon Kim join the pod to share their lates collaboration on a new C-N cross-coupling protocol which leverages a novel multifunctional template reagent. The work…
