The Age Reversal Project
by Orshi McNaughton
Hormone Therapy, GLP-1s & Peptides for Women’s Longevity | Dr. Shoma…
About this podcast
How close are we to actually reversing aging — and what will it take to get there?
The Age Reversal Project goes inside the rapidly evolving world of longevity, age-reversal science and healthy aging to explore the breakthroughs that could help us live longer, healthier and more capable lives.
Host Orshi McNaughton talks with the scientists, researchers, biotech founders, physicians and pioneers working at the edge of human longevity — from regenerative medicine, cellular reprogramming and gene therapy to AI, longevity therapeutics, emerging medications, advanced diagnostics and human trials.
We follow the technologies moving from the laboratory into the real world, the companies trying to turn longevity science into medicine, and the experiments testing what's possible in humans today. We also explore the interventions available now — from health optimization and biohacking to new approaches designed to extend healthspan, slow biological aging and potentially reverse aspects of aging itself. The Age Reversal Project is your front-row seat to the longevity frontier — and the race toward longevity escape velocity.
If you're fascinated by longevity, age reversal, biotechnology, AI, anti-aging science, regenerative medicine, healthspan and the future of human lifespan, this is where you'll meet the people building that future and follow the breakthroughs that could change how we age.
Episodes
The newest 20 of 26 episodes
- Hormone Therapy, GLP-1s & Peptides for Women’s Longevity | Dr. Shoma Datta-Thomas · 1 h 4 minDescription Hormone replacement therapy, testosterone, GLP-1 medications and peptides are changing how women approach menopause, metabolic health and longevity. Dr. Shoma…
- Can We Reverse Human Aging? Inside the $101M XPRIZE | Rabbit Hole #1 · 23 minCan we actually reverse human aging? XPRIZE has put $101 million behind that question, challenging scientists to demonstrate something far more meaningful than a younger…
- Microdosing GLP-1s: Can Less Actually Work Better? | Dr. Karen Mann · 52 minMicrodosing GLP-1s is quickly becoming one of the most talked-about topics in obesity medicine, but can taking less actually produce better long-term results for some people? In…
- Methylene Blue for Brain Fog, Anxiety and Low Energy | Dr. Scott Sherr, MD · 56 minMethylene blue is one of the most talked-about tools in biohacking for mitochondrial function, brain fog, and energy—and the nuance is in dosing, quality, and context. In this…
- Weight Loss Resistance in Midlife: What the Research Reveals I Dr. Bill Campbell, PhD · 1 h 13 minIf you’re strength training, eating “clean,” and still gaining fat or losing muscle after 40, it’s not just willpower—it’s physiology. In this episode we break down what actually…
- Women’s Hormones & the Future of Longevity Medicine | Dr. Amy Killen · 50 minThis episode explores how women’s hormones, aging, regenerative therapies, and technology are shaping the next era of longevity medicine. Dr. Amy Killen shares her evolution from…
- A Female Bodybuilder’s Guide to Muscle & Metabolism Over 50 I Carol Covino · 49 minDiscover how to build lean muscle, balance hormones, and reignite metabolism after 50. In this episode, you’ll learn the science behind muscle as a metabolic organ, how to train…
- How AI Is Revolutionizing Longevity Medicine | Jim Donnelly · 1 h 8 minDiscover how precision diagnostics, regenerative therapies, and AI are redefining the future of personalized healthcare. In this episode, you’ll learn how data-driven medicine…
- Hormonal Imbalances & Hair Thinning: What Every Woman Should Know | Faraz Khan · 1 h 0 minHair thinning, gray hair, and hair loss don’t have to be inevitable! In this episode, we explore the science of hair health and dive into the root causes of these issues—hormonal…
- Why Testosterone Levels Dropped 50% Worldwide | Shalin Shah · 1 h 3 minTestosterone levels have dropped by nearly 50% over the past 40 years, creating ripple effects in metabolism, mood, fertility, and longevity. In this episode, you’ll learn why…
- Closing the Gender Gap in Women’s Health Research I Katie Moore & Mackenzie De Jesus · 43 minWomen’s health research has historically overlooked critical differences in female biology. In this episode, Katie Moore and Dr. Mackenzie De Jesus join me to uncover the…
- How to Improve Vision & Brain Performance | Dr. Bryce Appelbaum · 1 h 6 minYour vision is more than just seeing clearly—it's a direct reflection of your brain function and overall health. In this episode, we explore the groundbreaking field of…
- Reverse Hashimoto’s and Autoimmunity Naturally | Ryan Monahan · 1 h 5 minIf you're struggling with fatigue, weight gain, brain fog, or unexplained symptoms despite “normal” labs, this episode will help you uncover what’s really going on. We explore…
- Inside the Biohacking Routine of a Mom and CEO I Lindsay O’Neill · 1 h 4 minWhat happens when a tech executive and mom of three uses biohacking to heal herself and her child from autoimmune dysfunction, chronic UTIs, and fatigue? Lindsay O’Neill shares…
- Gut Health: The Missing Key to Sustainable Weight Loss | Joel Greene · 1 h 9 minIf you're stuck in the cycle of restrictive dieting and rebound weight gain, your gut may be the root cause. In this eye-opening episode, Joel Greene shares how gut diversity…
- Unlocking Your Inner Strength: The Right Way to Do Cold Therapy for Women | Kristin Weitzel · 42 minCold therapy can be a powerful tool for fat loss, metabolic health, stress resilience, and recovery—but women need a different approach than men. In this episode, we break down…
- Sleep Optimization & Circadian Health Explained | Mollie Eastman · 47 minIf you're exhausted but can't sleep, stuck in a cycle of sleeping pills, or struggling to fix your sleep despite trying everything—this episode is for you. Sleep expert Molly…
- Real Talk on Perimenopause, Hormones, and HRT I Dr. Salome Masghati · 1 h 6 minThis episode reveals the hidden risks of hormonal birth control, how it alters your gut, mood, and long-term health, and why most OB/GYNs are missing the mark on hormone therapy…
- Osteoporosis Prevention & Hormone Replacement Therapy I Dr. Doug Lucas · 54 minOsteoporosis isn’t just a concern for older women—it often starts much earlier than you think. Bone health is deeply connected to hormones, metabolism, and nutrition, and the…
- A Holistic Take on GLP-1s for Weight Management | Nat Niddam · 58 minStruggling to lose weight despite a healthy lifestyle? In this episode, holistic nutritionist Nat Niddam joins us to uncover the science and strategy behind GLP-1 weight-loss…
