Aging-US
by Aging Podcast
Partial Reprogramming Linked to Tissue-Specific Rejuvenation Signals…
About this podcast
Aging is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Our mission is to serve as a platform for high-quality research that uncovers the cellular, molecular, and systemic processes underlying aging, and translates these insights into strategies to extend healthspan and delay the onset of chronic disease.
Read about the Aging Scientific Integrity Process: https://aging-us.com/scientific-integrity
Episodes
The newest 50 of 500 episodes
- Partial Reprogramming Linked to Tissue-Specific Rejuvenation Signals and Potential Risks · 4 minBUFFALO, NY — November 12, 2026 — A new #research paper was #published in Volume 18 of Aging on October 27, 2026, titled “Investigating the efficacy and toxicity of partial in…
- New Aging Framework Shifts Focus of Late-Life Rejuvenation to Systemic Signaling · 5 minBUFFALO, NY — November 10, 2026 — A new #research perspective was #published in Volume 18 of Aging on October 20, 2026, titled “From hyperfunction to systemic amplification…
- Epigenetic Aging Signal Is Linked to Brain Changes Associated With Dementia Risk · 12 minTwo people can be the same chronological age and yet differ considerably in how quickly their bodies appear to be aging. Scientists have developed “epigenetic clocks” that use…
- Ferroptosis-Related Genes in Muscular Dystrophy May Offer New Insights Into Muscle Aging · 6 minBUFFALO, NY — November 5, 2026 — A new #research paper was #published in Volume 18 of Aging on October 14, 2026, titled “Ferroptosis-related hub genes and immune infiltration…
- New Aging Framework Proposes Epigenetic Regulation as a Major Limit on Human Lifespan · 11 minBUFFALO, NY — November 3, 2026 — A new #review was #published in Volume 18 of Aging on October 9, 2026, titled “The polycentric aging framework: epigenetic regulation as a…
- Longevity & Aging Series (S4, E8): Rose S. Al-Saadi · 24 minIn this episode of the Longevity & Aging Series (S4, E8), Rose S. Al-Saadi from the Institute of Ecology and Evolution, University of Oregon, Eugene, joins host Dr. Yuan Zhao to…
- Small Extracellular Vesicles Found to Spread Cellular Senescence in Models of Aging · 10 minBUFFALO, NY — October 29, 2026 — A new #research paper was #published in Volume 18 of Aging on October 8, 2026, titled “Small extracellular vesicles as mediators of paracrine…
- Body Composition, Rather Than Masculine Physical Traits, Linked to Aging Markers in Middle-Aged Men · 9 minBUFFALO, NY — October 28, 2026 — A new #research paper was #published in Volume 18 of Aging on October 6, 2026, titled “Body composition, but not morphological masculinity, is…
- Progerin Expression Creates a Yeast Model of Premature Aging · 16 minAging is shaped not only by changes in DNA and metabolism but also by the gradual accumulation of proteins that cells struggle to remove. One striking example is Progerin, an…
- Hypomagnetic Fields Extend Survival but Reduce Mobility in Fly Model of Parkinson’s Disease · 9 minBUFFALO, NY — October 22, 2026 — A new #research paper was #published in Volume 18 of Aging on September 23, 2026, titled “Hypomagnetic fields modulate lifespan, physical ability…
- mTOR Signaling Emerges as a Key Regulator of Aging, Highlighting Need for Targeted Interventions · 10 minBUFFALO, NY — October 20, 2026 — A new #review was #published in Volume 18 of Aging on September 19, 2026, titled “mTOR signaling in aging: from causality to geroprotective…
- Behind the Study: Drug Combo Targets Cancer & Senescent Cells, Extends Lifespan in Old Mice · 12 minAging Editorial Board member Dr. Irina Conboy and Dr. Zachery Robinson from the Department of Bioengineering and QB3 Institute at the University of California, Berkeley, present…
- Longevity & Aging Series (S4, E7): Dr. Irina Conboy and Dr. Zachery Robinson · 36 minIn this episode of the Longevity & Aging Series (S4, E7), Dr. Irina Conboy and Dr. Zachery Robinson from the Department of Bioengineering and QB3 Institute at UC Berkeley, CA…
- Editors’ Choice: Social determinants of health and risk of dementia in people with and without type 2 diabetes · 2 minThis month’s Editor’s Choice features the #research paper recently #published in Aging, titled “Social determinants of health and risk of dementia in people with and without type…
- New Control Theory Framework Proposes a Safer Approach to Aging Drug Discovery · 9 minBUFFALO, NY — October 15, 2026 — A new #research paper was #published in Volume 18 of Aging on September 16, 2026, titled “Control theory of aging and longevity for…
- New Gene–Phenotype Catalogue Maps the Genetic Landscape of Premature Aging · 14 minRare genetic disorders that cause features of aging to appear much earlier than expected can offer an unusual window into the biology of human aging. Yet information about these…
- Targeting PLA2G15 Reduces Senescence and Alters Lipid Metabolism in Kidney Cells · 9 minBUFFALO, NY — October 13, 2026 — A new #research paper was #published in Volume 18 of Aging on September 16, 2026, titled “Targeting phospholipase Pla2g15 reduces long-chain BMP…
- Behavioral Complexity Could Offer New Insights Into Aging and Frailty · 7 minBUFFALO, NY — October 8, 2026 — A new #commentary was #published in Volume 18 of Aging on September 12, 2026, titled “Complexity, variability, and the behavioral layer of…
- Mini-GRID Radiotherapy Reduces Senescence While Preserving Growth Inhibition in Glioma Cells · 7 minBUFFALO, NY — October 6, 2026 — A new #research paper was recently #published in Volume 18 of Aging, titled “Spatially fractionated mini-GRID radiotherapy differentially…
- Aging Supports the 11th International Cell Senescence Association Conference · 2 minBUFFALO, NY — October 5, 2026 — Aging is pleased to support the 11th International Cell Senescence Association (ICSA) Conference, taking place November 3–5, 2026, at Seoul…
- Adverse Social Determinants Linked to Higher Dementia Risk in People With Type 2 Diabetes · 6 minBUFFALO, NY — October 1, 2026 — A new #research paper was #published in Volume 18 of Aging on September 10, 2026, titled “Social determinants of health and risk of dementia in…
- ATF5 Helps Preserve Mitochondrial Quality and Muscle Endurance During Aging · 14 minAging is commonly associated with the gradual loss of skeletal muscle mass and function. While preserving muscle mass is important, muscle health also depends on the mitochondria…
- Developmental Senescence Emerges as a Candidate Mechanism in CHARGE Syndrome · 7 minBUFFALO, NY — September 29, 2026 — A new #review was #published in Volume 18 of Aging on September 8, 2026, titled “Developmental senescence misregulation in congenital…
- Longevity & Aging Series (S4, E6): Dr. Adam Bohnert · 38 minIn this episode of the Longevity & Aging Series (S4, E6), Dr. Adam Bohnert from the Department of Biological Sciences at Louisiana State University (Baton Rouge, LA) joins host…
- Exceptional Longevity Across Species Linked to DNA Maintenance, Stemness and Stress Resistance · 7 minBUFFALO, NY — September 24, 2026 — A new #review was #published in Volume 18 of Aging on September 8, 2026, titled “How to live for centuries: common denominators of organisms…
- The “Guardian Paradox” Links Chronic DNA Damage Response to Aging · 9 minBUFFALO, NY — September 21, 2026 — A new #review was #published in Volume 18 of Aging on August 31, 2026, titled “The guardian paradox: DNA damage response overactivation as an…
- EDITORS’ CHOICE: Human-relevant Ptpn6 mutation alters immune and hepatic functions during aging · 2 minA research paper recently published in Aging, titled “Human-relevant Ptpn6 mutation alters immune and hepatic functions during aging,” investigated how a human-relevant mutation…
- Human-Relevant Ptpn6 Mutation Reveals Complex Links Between Immunity, Metabolism and Liver Aging · 7 minBUFFALO, NY — September 16, 2026 — A new #research paper was #published in Volume 18 of Aging on August 28, 2026, titled “Human-relevant Ptpn6 mutation alters immune and hepatic…
- Evidence for Cellular Senescence as a Driver of Aging Stronger Than for Somatic Mutations · 7 minBUFFALO, NY — September 14, 2026 — A new #review was #published in Volume 18 of Aging on August 26, 2026, titled “Assessing mechanisms and evidence of a causal role for cellular…
- Misha Blagosklonny’s Ideas Reshaped Thinking About Aging · 8 minScientific progress often begins with questioning assumptions that have shaped a field for decades. Few researchers embodied this approach as strongly as Dr. Mikhail “Misha”…
- Reduced Insulin/IGF-1 Signaling Dramatically Extends Male Lifespan in C. elegans · 5 minBUFFALO, NY — September 10, 2026 — A new #research paper was #published in Volume 18 of Aging on August 24, 2026, titled “Disruption of the insulin/IGF-1 signaling pathway in…
- Three Herbal Extracts Protect Mitochondrial Function in a Cellular Model of Parkinson’s Disease · 8 minBUFFALO, NY — September 9, 2026 — A new #research paper was #published in Volume 18 of Aging on August 13, 2026, titled “Protective effects of three herbal extracts on…
- Behind the Study: How Aging Impairs Tuberculosis Clearance · 8 minDr. Falak Pahwa, Dr. Ranjan Kumar Nanda, and Mr. Ashish Gupta from the International Centre for Genetic Engineering and Biotechnology (ICGEB) in New Delhi, India, discuss their…
- Indy Gene Reduction Linked to Healthier Gut Microbiota and Longer Lifespan in Fruit Flies · 5 minBUFFALO, NY — September 3, 2026 — A new #research paper was published in Volume 18 of Aging on August 12, 2026, titled “Indy reduction decreases aging-related dysbiosis in…
- Developmental Programs Could Help Drive the Aging Process · 14 minWhy do we age? For decades, one of the dominant explanations has been that cells and tissues gradually accumulate molecular damage until they can no longer function normally. DNA…
- Higher TMAO Levels Linked to Cardiometabolic Risk and Brain Atrophy in Older Adults · 5 minBUFFALO, NY — August 31, 2026 — A new research paper was published in Volume 18 of Aging on August 11, 2026, titled “TMAO is associated with higher age, cardiometabolic risk…
- Metformin Emerges as a Promising Candidate at the Intersection of Aging and Longevity · 7 minBUFFALO, NY — August 26, 2026 — A new #review was #published in Volume 18 of Aging on August 10, 2026, titled “Metformin at the convergence of aging and longevity.” The review…
- Targeting POLG Reduces Breast Cancer Stemness Through Mitochondrial Dysfunction · 7 minBUFFALO, NY — August 24, 2026 — A new research paper was published in Volume 18 of Aging on August 8, 2026, titled “Investigating POLG-driven modulation of cancer stemness: a…
- Aging Partners with Aging Research and Drug Discovery Meeting (ARDD) as Media Partner · 1 minBUFFALO, NY — August 24, 2026 — Aging is pleased to announce its partnership as a media partner of the 13th Aging Research and Drug Discovery Meeting (ARDD), taking place October…
- EDITORS’ CHOICE: Slowing intervertebral disc aging in mice through long-term systemic treatment · 2 minA #Research paper recently #Published in Volume 18 of Aging, titled “Slowing intervertebral disc aging in mice through long-term systemic treatment with the senolytic…
- Transcriptomic Aging Clock Reveals Age-Related Molecular Patterns in Opioid Dependence · 9 minBUFFALO, NY — August 12, 2026 — A new #research paper was #published in Volume 18 of Aging on July 27, 2026, titled “Transcriptomic aging clock analysis identifies key genes in…
- Misha Blagosklonny’s Scientific Legacy Continues to Shape Modern Aging Research · 5 minBUFFALO, NY — August 10, 2026 — A new #essay was #published in Volume 18 of Aging on August 6, 2026, titled “Misha Blagosklonny: a life of ideas.” The article was written by…
- Hyperfunction Theory Offers a New Perspective on Why We Age · 6 minBUFFALO, NY — August 6, 2026 — A new #research perspective was #published in Volume 18 of Aging on July 24, 2026, titled “A brief history of the hyperfunction theory of aging and…
- Longevity & Aging Series (S4, E5): Dr. Kan Cao · 32 minIn this episode of the Longevity & Aging Series (S4, E5), Dr. Kan Cao of the Department of Cell Biology and Molecular Genetics at the University of Maryland joins host Dr. Yuan…
- Fatty Liver Disease Linked to Early Cardiovascular and Cognitive Changes · 5 minBUFFALO, NY — August 5, 2026 — A new #research paper was #published in Volume 18 of Aging on July 23, 2026, titled “Adipo-neuroinflammation, cognitive impairment and surrogate…
- Hypertonic Saline Plus Furosemide Improves Heart Failure Biomarkers in Randomized Trial · 9 minHeart failure remains one of the leading causes of hospitalization among older adults worldwide. During episodes of acute decompensated heart failure (ADHF), excess fluid builds…
- New Drug Combination Targets Cancer and Senescent Cells While Extending Lifespan in Old Mice · 5 minBUFFALO, NY — August 3, 2026 — A new #research paper was #published in Volume 18 of Aging on July 17, 2026, titled “Selective targeting of cancer and senescence via shared…
- Italy Proposes a Healthspan-Focused Framework for Healthy Aging · 6 minBUFFALO, NY — July 30, 2026 — A new #research perspective was #published in Volume 18 of Aging on July 16, 2026, titled “Towards integration of healthspan strategies into the…
- Senolytic PROTAC Slows Age-Related Intervertebral Disc Degeneration in Male Mice · 5 minBUFFALO, NY — July 27, 2026 — A new #research paper was #published in Volume 18 of Aging on July 13, 2026, titled “Slowing intervertebral disc aging in mice through long-term…
- New Surface Marker Could Advance Precision Therapies for Type 2 Diabetes · 5 minBUFFALO, NY — July 23, 2026 — A new #research paper was #published in Volume 18 of Aging on July 8, 2026, titled “TM4SF1 is a surface marker of senescent pancreatic β-cells.”…







