Health Longevity Secrets
by Robert Lufkin MD
Latest episode
Are Peptides Legal Now? What Actually Changed
Are Peptides Legal Now? What Actually Changed
About this podcast
The health advice you're getting isn't working. Want to know what the experts actually do for themselves?
Health Longevity Secrets reveals the real science behind longevity, metabolic health, fasting, and disease reversal—the protocols that researchers and physicians use in their own lives, not just what they tell patients.
Robert Lufkin MD is a medical school professor, practicing physician, and New York Times bestselling author. After reversing his own chronic disease through lifestyle medicine, he's on a mission to share what actually works.
Each episode features in-depth interviews with world-class scientists, doctors, and biohackers who share their personal health strategies—no sponsored talking points, just real answers.
Your health transformation starts here.
Episodes
The newest 50 of 290 episodes
- Are Peptides Legal Now? What Actually Changed · 8 minOn October 28, 2026, HHS said it will allow pharmacies to compound six popular peptides: BPC-157, TB-500, KPV, MOTS-c, Semax, and Epitalon. Not one of them is FDA approved, and…
- Your Mitochondria Are Eating You Alive (How to Rebuild Them) | Oct 27, 2026 · 8 minInside every one of your cells live tiny ancient bacteria called mitochondria. When they fail, and they fail decades before you feel sick, they drive cancer, Alzheimer's, heart…
- Elizabeth Holmes's Blood Test Dream Is Coming True Without Her · 8 minElizabeth Holmes went to prison for promising hundreds of blood tests from a single drop of your finger. Some of what she promised is now FDA cleared, and some of it may never be…
- EXPLAINER: Did Plague Just Escape From a Russian Lab? · 8 minA young scientist died in a Russian plague lab. Officials deny an accident. Is biowarfare a real threat, or is the bigger risk something else? Robert Lufkin MD looks at the death…
- EXPLAINER: How To Live To 117 · 9 min · Episode 302She lived to 117 — and when scientists sequenced everything from her genome to her gut bacteria, they found a paradox that rewrites what aging has to look like. In this episode…
- Ozempic Face: Why Weight Loss Can Make You Look Older | Kay Durairaj MD · 45 min · Episode 301A facial plastic surgeon reveals the MRI data on "Ozempic face," why repeated masseter Botox can thin the jawbone, and the topical rapamycin resetting skin cells to a 20-year-old…
- EXPLAINER: Will AI Cure All Disease? · 10 min · Episode 300Will AI cure all disease? 90% of biomedical papers published in December 2025 show signs of AI assistance — and the Nobel laureate behind AlphaFold says AI could help end all…
- Ultrasound to Calm the Nervous System | Jon Hacker · 42 min · Episode 299Modern technology is tricking your nervous system into fight-or-flight — and it's decently profitable to keep you there. Jon Hacker, CEO of NeurGear, explains how focused…
- EXPLAINER: Will mRNA Vaccines Cure Cancer? · 9 min · Episode 298For the first time in history, a personalized mRNA cancer vaccine has passed a Phase 3 clinical trial. Robert Lufkin MD breaks down the Moderna/Merck melanoma result, how a…
- The Alzheimer's Lie: It's Not The Amyloid | David Perlmutter MD · 49 min · Episode 279Neurologist David Perlmutter MD says the beta-amyloid theory of Alzheimer's is wrong — and the real culprit is your brain's own immune cells. In this episode of Health Longevity…
- EXPLAINER: Human Age Reversal Has Begun · 8 min · Episode 280They just injected youth genes into a human eye. On June 9, 2026, a patient with glaucoma became the first human ever dosed with ER-100 — an epigenetic reprogramming gene therapy…
- Your Beliefs Control Your Genes | Bruce Lipton PhD · 1 h 0 min · Episode 297What if your genes aren't your destiny? Cell biologist Bruce Lipton PhD — the former medical school professor whose cloned stem cell research helped pioneer epigenetics, and…
- EXPLAINER: The Longevity IV That Killed a 27-Year-Old · 8 min · Episode 278A healthy 27-year-old walked into a Bronx wellness center for an NAD+ "longevity infusion" — and was dead within the hour. The man holding the needle wasn't licensed to practice…
- Heart Surgeon: It's Not Cholesterol — It's Metabolic Health | Philip Ovadia MD · 47 min · Episode 296A cardiac surgeon who's performed thousands of open-heart operations says most of his patients didn't have to be there — and the culprit isn't cholesterol, it's metabolic health…
- There's No Such Thing as a Weight Problem | Ben Azadi · 45 min · Episode 276"There's no such thing as a weight problem — it's a weight symptom." Ben Azadi joins Robert Lufkin MD to dismantle the calorie myth and reveal the metabolic root cause underneath…
- The Nerve in Your Ear That Controls Stress | Jane Ollis (Sona) · 47 min · Episode 295What if a single nerve in your ear could shift you out of fight-or-flight in 10 minutes? Jane Ollis explains why your vagus nerve and HRV may be the most overlooked levers for…
- EXPLAINER: Glucosamine and Alzheimer's: Protection or Poison? · 9 min · Episode 274The same glucosamine pill millions take for joint pain may protect a healthy brain — and accelerate Alzheimer's in a brain already in decline. Here's the science. In this episode…
- What If The Pain Is Actually The Fuel? | Ben Barbic · 42 min · Episode 273What if the pain you've been trying to escape is actually the fuel you've been looking for? Recording artist Ben Barbic walked away from alcohol, nicotine, and blood pressure…
- EXPLAINER: Does Creatine Cause Cancer? What the Science Actually Says · 10 min · Episode 294Creatine causes cancer to spread — that headline is built on a real mouse study. But what does the human data actually say? In this solo explainer, Dr. Robert Lufkin breaks down…
- The Smart Toilet That Could Detect Cancer Before You Know You Have It | Scott Hickle (Throne) · 42 min · Episode 293Colorectal cancer is now the #1 cancer killer in Americans under 50 — and roughly 60% of cases are diagnosed at stage III or IV. What if your toilet could spot the earliest sign…
- EXPLAINER: Sleep Isn't For Muscle Repair — Here's What It's Actually For · 12 min · Episode 292Forget muscle repair. The reason sleep actually transforms your health is happening inside your skull every night — and it's not what Matthew Walker's TED Talk made famous. In…
- Are We In A Longevity Revolution? — David Donnelly (Director, Forever Young) · 44 min · Season 1 Episode 269What if the longevity revolution isn't really a science problem, but a human one we're completely unprepared for? In this episode of Health Longevity Secrets, Robert Lufkin MD…
- EXPLAINER: ANKTIVA- The Next Great Longevity Drug? · 13 min · Episode 268There's a single number on your routine blood test that predicts your risk of dying from cancer, heart disease, and infection better than cholesterol — and an FDA-approved drug…
- The Army Ranger Who Found Magic Mushrooms Save Lives — Neil Markey (Beckley Retreats) · 48 min · Season 1 Episode 267What if the same symptoms we see in combat veterans — the broken sleep, the irritability, the brain fog — were already quietly spreading through the healthiest…
- EXPLAINER: 5 Longevity Myths the Latest Science Has Debunked · 9 min · Season 1 Episode 266Five longevity beliefs that millions have followed for decades have just been overturned by the latest research. Some of these will surprise you. In this explainer, Robert Lufkin…
- Perimenopause Is the Inflection Point Breaking Women's Health — Dr. Mayoni Gooneratne · 44 min · Season 1 Episode 265What if the most dangerous metabolic inflection point in a woman's entire life is the one we've been taught to simply endure? In this episode of Health Longevity Secrets, Robert…
- EXPLAINER: What Happens to Your Body in 5 Days Without Ultra-Processed Food · 8 min · Episode 264Ultra-processed food makes up over half the calories Americans eat - and over 60% for kids. Here's what the research shows happens inside your body in the first 5 days after you…
- The 91-Year-Old Physicist Betting His Body on Mitochondrial Transplant | John Cramer PhD · 59 min · Episode 263What if aging isn't a hundred separate problems but a single one — an energy crisis inside the tiny power plants of every cell? At 91, Dr. John G. Cramer is betting his own body…
- EXPLAINER: 3 Blood Tests Your Doctor Skips (That Predict Heart Attacks & Alzheimer's) · 9 min · Episode 262Your doctor orders a lipid panel every year — but 3 cheap blood tests predict heart disease, diabetes, and even dementia far better than cholesterol, and most doctors never order…
- Your Phone Is Rewriting Your Biology — Daniel DeBaun (Former Bell Labs Engineer) · 50 min · Season 1 Episode 261What if the single device you hold closest to your body for 10+ hours a day is quietly rewriting your biology — and your grandchildren's? In this episode of Health Longevity…
- EXPLAINER: Medicine's Forgotten Biomarker - The Homocysteine Story Your Doctor Missed · 14 min · Episode 260In 1969, Harvard pathologist Kilmer McCully discovered elevated homocysteine causes arterial damage and heart disease. He was forced out of Harvard. The Framingham Heart Study…
- AI-Powered Longevity Science — One Gene to Reverse Aging? | Daniel Ives PhD · 1 h 25 min · Episode 259What if an AI could run centuries of aging experiments in a year? Dr. Daniel Ives, CEO of Shift Bioscience, explains how his team used a virtual cell to discover SB000 — a single…
- EXPLAINER: 90% of Americans Have This Disease — And Most Have Never Heard of It · 12 min · Episode 258In October 2023, the American Heart Association officially admitted something that changes everything: heart disease, kidney disease, and diabetes are not separate conditions —…
- Keto Saved My Life — The Future of Metabolic Medicine | Nick Norwitz PhD MD · 52 min · Episode 257A ketogenic diet put his ulcerative colitis into complete remission — off all medications, confirmed on colonoscopy. Dr. Nick Norwitz (PhD Oxford, MD Harvard) explains why…
- EXPLAINER: The Magnesium LIE — Why Your Blood Test Is Missing 99% of the Problem · 15 min · Episode 256Your doctor says your magnesium is normal. But that test measures less than 1% of your body's total magnesium. Nearly half of US adults are deficient in the mineral required for…
- Can a Transplant Cure Aging? | Catherine Baucom MD PhD · 49 min · Episode 255Imagine treating chronic disease by restoring the cell's energy engines rather than chasing symptoms. That's the bet behind mitochondrial organelle transplantation — delivering…
- EXPLAINER: Walking Won't Burn Fat (Here's What It Actually Does) · 12 min · Episode 254Walking videos are everywhere — "walk 10,000 steps and melt belly fat." The conclusion is right: walking does reduce body fat. But the explanation is completely wrong. Your body…
- The Longevity Nerve: The Missing Link in Stress, Aging & Brain Health | Elisabetta Burchi MD · 1 h 1 min · Episode 253What if one nerve quietly connects your brain to your heart, gut, immune system, and even how long you live? Dr. Elisabetta Burchi explains why the vagus nerve may be the missing…
- A Glucose Sensing Watch | Sabih Chaudhry PhD · 36 min · Episode 252Ever wished continuous glucose data didn’t require needles, adhesives, or a prescription? We sit down with Sabih Chaudhry, PhD, founder of AFON Technology, to unpack GlucoWare—a…
- The $101 Million Race to Solve Longevity | Jamie Justice PhD · 1 h 4 min · Episode 251Dr. Jamie Justice is the Executive Director of XPRIZE Healthspan - a $101 million, 7-year global competition to extend human healthspan by developing therapies that restore…
- How To Reverse Alzheimer's | Heather Sandison ND · 46 min · Episode 250Dr. Heather Sandison was told in medical school that suggesting you could help someone with Alzheimer's was promoting false hope. Then she ran a clinical trial and 74% of…
- The Sugar Addiction Lie | Christine Trimpe · 43 min · Episode 249Christine Trimpe was morbidly obese, pre-diabetic, and couldn't walk a half-mile mountain trail. Ten years later, she's lost over 100 pounds, reversed fatty liver disease and…
- We’re Not Sick. We’re Being Sold | David Etheridge · 36 min · Episode 248A high calcium score, a stack of prescriptions, and the nagging sense that “healthy eating” wasn’t working—David Etheridge’s story captures what millions feel but rarely decode…
- Why Am I Always Hungy? | Jason Fung MD · 53 min · Episode 247What if the real lever for lasting weight loss isn’t calories, but hunger itself? We sit down with Dr. Jason Fung to unpack why willpower-based diets fail and how hormones like…
- Why Your Brain Doesn’t Have to Age | Majid Fotuhi MD · 50 min · Episode 246Think your brain has to slow down with age? We push back hard with science, stories, and a step-by-step plan that has helped patients regain clarity in weeks, not years. Our…
- The Movie Amazon Doesn’t Want You to See | Vinny Lingham · 51 min · Episode 245A tech founder’s health fell apart, and the fix didn’t come from a supplement stack or another glossy wellness trend. It started with a hard look at seed oils, blood sugar…
- Ancient Health Secret Revealed | Shivani Gupta PhD · 45 min · Episode 244Pain that creeps in, brain fog that lingers, weight that resists every effort—what if the culprit isn’t “just getting older,” but inflammaging? We sit down with Dr. Shivani…
- How Ancestral Wisdom Transforms Our Health · 44 min · Episode 243What if the most powerful biohack is simply getting the morning sun in your eyes and letting your wearables prove it works? We explore Medicine 4.0 with Steven Stavrou DCM, a…
- When ‘Normal Labs’ Are Unhealthy | Sandeep Palakodeti MD · 46 min · Episode 242Feeling “fine” is not a plan. We sit down with Dr Sandeep Palakodeti —an Ivy League–trained internist who left elite institutions—to unpack why so much of healthcare reacts to…
- Is Oxygen the Root Cause of Chronic Disease? · 42 min · Episode 241What if the core of fatigue, brain fog, and “getting old” is really an oxygen problem? We sit down with Brad Pitzele to unpack how exercise with oxygen therapy (EWOT) and red and…
