About this podcast
Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine and have special guests talking about their area of expertise! This podcast is made for educational purposes. The content provided in this podcast, and in any linked materials, is not intended and should not be construed as medical advice and should not be used to diagnose or treat any medical condition. We try to stay away from opinions but all opinions represent our own and not of any entity we work for. Please keep this in mind as you enjoy the podcast!
Episodes
The newest 20 of 107 episodes
- New: VASSPR · 46 min · Season 1 Episode 104Episode 104! In this episode we talk about VASSPR or vasopressin timing in septic shock published in JAMA by Peltan et al 2026! Only one article for the next few episodes as we…
- LIVE @ CHEST2026: Sigh breaths and GLP-1 · 46 min · Season 1 Episode 103Episode 103 LIVE from CHEST in Phoenix. It was a wonderful conference and thanks for everyone who came and joined us! In this episode we talk about lung recruitment during sigh…
- New/Old: RATE and CESAR · 49 min · Season 1 Episode 102Episode 102! In this episode we talk about ECMO anticoagulation strategies with RATE and go back in time to talk about the original landmark trial for ECMO in CESAR RATE…
- Old/New: TTM2 and ICECAP · 44 min · Season 1 Episode 101Episode 101! In this episode we talk about targeted temperature management starting with TTM2 to set the stage and moving towards ICECAP published by Muerer et al in JAMA August…
- New: Olanzapine vs Dex and a look back · 46 min · Season 1 Episode 100Episode 100! Can't believe we made it here. 100 episode of trying to fit into Todd's triple booked schedule. This episode we do a little reminiscing about the past 3 years of…
- NEXIS and Mailbag · 39 min · Season 1 Episode 99Episode 99! In this episode we talk about Nutrition and Exercise in Critical Illness published in AJRCCM June 2026 by Needham et al. A shorter episode today as we're dealing with…
- Old/New: EUPHRATES and Tigris · 55 min · Season 1 Episode 98Episode 98! We talk about polymyxin B filtration of endotoxin for patients with septic shock in EUPHRATES which sets the stage for Tigris. We also butcher Mesopotamian history…
- New/New: MARCH and Tele-Rehab · 56 min · Season 1 Episode 97Episode 97! In this episode we talk about mucolytics for patients with difficult to clear secretions on the ventilator and the effects of a tele ICU rehabilitation intervention!…
- New/New: ARISE-FLUIDS and VICTORY (+mail) · 1 h 5 min · Season 1 Episode 96Episode 96. In this episode we talk about ARISE FLUIDS (early pressors vs early fluids) and VICTORY (high dose Vitamin C in severe burn) both simultaneously presented and…
- New/New: BiHCA and SODa-BIC · 52 min · Season 1 Episode 95Episode 95! In this episode we talk about "Sodium Bicarbonate for In-Hospital Cardiac Arrest" by Granfeldt et al and "Sodium Bicarbonate for Critically Ill Adults with Metabolic…
- CCR26 and the unpublished results presentations · 55 min · Season 1 Episode 94Episode 94! In this episode we give some general reactions to the CCR conference, discuss our impact on the critical care world, and talk briefly about 3 of the presentations…
- NEW: ATS 2026 and Hantavirus? · 1 h 2 min · Season 1 Episode 93Episode 93! In this episode we go over TOWAR or "Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage" by Sperry et all published in NEJM and "Remote…
- New: R2D2 · 42 min · Season 1 Episode 92Episode 92! In this episode we talk about "Restrictive vs Liberal Physical Restraint Strategies in Critically Ill Patients" published in JAMA by Sonneville et al April 2026! R2D2…
- New: 4D · 44 min · Season 1 Episode 91Episode 91! In this episode we talk about "Dexmedetomidine for treatment of hyperactive delirium in non-intubated ICU patients" published by Godet et al in Intensive Care…
- New: 2026 Sepsis Guidelines · 1 h 2 min · Season 1 Episode 90Episode 90! In this episode we talk about the 2026 Surviving Sepsis Campaign Guidelines lead by Prescott et all and published in Critical Care Medicine in March of 2026! We…
- New: Hi-PEITHO · 48 min · Season 1 Episode 89Episode 89! In this episode we talk about HI-PEITHO or catheter directed thrombolysis versus conventional anticoagulation for intermediate risk pulmonary embolism. This was…
- New/New: PE and CPR Guidelines · 47 min · Season 1 Episode 88Episodes 88! In this episode we talk about guidelines recently released for the management of pulmonary embolism and cardiac arrest! A little hap hazard of an episode as we jump…
- Old/New: ALBIOS and ARISS · 47 min · Season 1 Episode 87Episode 87! In this episode we talk about Albumin with two related studies, ALBIOS ("Albumin replacement in patients with severe sepsis or septic shock" by Caironi et al) and…
- New: PreVent2 · 48 min · Season 1 Episode 86Episode 86! In this episode we talk about endotracheal tubes or "Hospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes…
- New: LIBERATE-D with Eddie Siew · 58 min · Season 1 Episode 85Episode 85! In this episode we go over LIBERATE-D or "A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury" by Liu et al in…







