About this podcast
From the UK to the USA - Melanoma Matters is on a mission!
Hosts James Larkin and Sapna Patel are spreading the word on melanoma, one podcast at a time. Tune in for a critical review of the literature and a discussion of how we incorporate the data into our practices...across the pond(s).
#MelanomaMatters video podcast
Episodes
The newest 20 of 95 episodes
- Preview of a PREVIEW · 2 min · Season 2 Episode 89ADCs are coming in melanoma and James is stunned into silence for 45s
- Ep 89: PREVIEW ESMO Annual Meeting: 2026 Madrid · 15 min · Season 2 Episode 89James and Sapna discuss all the meanings of the word "pike" and preview the presentations they are looking forward to at the 2026 ESMO Annual Congress from the Melanoma and Skin…
- Ep 88: Negative Adjuvant Doublet Studies (CM915, KV010, RELA098) · 22 min · Season 2 Episode 88Melanoma Matters: Why Adjuvant Doublet Immunotherapy Fell Short Hobbies - James wishes he was surfing more This episode breaks down three negative adjuvant melanoma trials…
- Ep 87: INTerpath-001 Press Release - August 2026 · 13 min · Season 2 Episode 87In this episode, Sapna and James discuss the INTerpath-001 press release describing primary endpoint (RFS) and key secondary endpoint (DMFS) findings from the randomized phase 3…
- Ep 86: Tudriqev (RP1) FDA Approval · 53 min · Season 2 Episode 86In this episode, James and Sapna debate how to pronounce the newest FDA approved treatment for melanoma: T-U-D-R-I-Q-E-V They discuss the FDA Cell and Gene Therapy Advisory…
- Ep 85: Surgical considerations for TIL · 29 min · Season 2 Episode 85In this episode, Sapna and James talk tv shows - The Gambler and His Cowboys, Brassic... They discuss the paper from NKI on surgical considerations for TIL harvest published in…
- Ep 84: Merlin CP-GEP and Castle i31-SLNB tests · 35 min · Season 2 Episode 84In this episode, the chin dimple is front and center. James explains the wizarding home of Tintagel in Cornwall to Sapna, situated on a lovely promontory. This episode explores…
- Ep 83: Guest Megan Othus and Time of Day Administration · 40 min · Season 2 Episode 83James and Sapna welcome Megan Othus, Professor of Biostatistics at the Fred Hutch Cancer Center and one of the key statisticians at SWOG. Megan talks about growing up in the PNW…
- Ep 82: Best of ASCO: 2026 · 1 h 4 min · Season 2 Episode 82In this episode, James & Sapna tease the size of ASCO and ESMO and number of simultaneous publications. They review the most impactful melanoma and Merkel cell carcinoma…
- Live from ASCO 2026: a preview · 6 min · Season 2 Episode 82James & Sapna sent a brief message from ASCO 2026 about what they are looking forward to hearing at the meeting. OptimUM-02 ADAM KN-942 Neoadjuvant pilot studies ... and more
- Ep 81: IGNYTE trial (RP1 + nivo) · 33 min · Season 3 Episode 81SummaryThe conversation covers the published data from the IGNYTE study - RP1 + nivolumab: response rate and safety profile, RNA-seq analysis, and toxicity. The key takeaways…
- Ep 80: 2025 Holiday Special · 36 min · Season 2 Episode 80Summary Happy Holidays and Festive Season Everyone! In this episode of Melanoma Matters, hosts Sapna Patel and James reflect on their "cultural" experiences over the past year…
- Ep 79: coBRIM, COMBI-d 5-year follow-up · 36 min · Season 2 Episode 79Summary In this episode of Melanoma Matters, James awaits an invitation to a film premiere (The Penguin Lessons) and we all await a picture of him in his tuxedo! Sapna and James…
- Ep 78 TRAILER: MEK inhibitor trials · 1 min · Season 2 Episode 78Enjoy this short trailer on MEK inhibitor monotherapy trials in melanoma
- Ep 78: MEK inhibitor trials (METRIC, NEMO, pimasertib) · 37 min · Season 2 Episode 78Summary So many shoutouts in this episode of Melanoma Matters! Sapna and James engage in a lively discussion about MEK inhibitors as monotherapy treatment. They explore the…
- Ep 77: Guest Merrick Ross · 45 min · Season 2 Episode 77Summary In this episode of Melanoma Matters, hosts James Larkin and Sapna Patel engage with Merrick Ross, a seasoned surgical oncologist, discussing his background, the…
- Ep 76: KEYNOTE 054 7-year follow-up · 29 min · Season 2 Episode 76Summary In this Episode, hosts James & Sapna go into the 7-year follow-up from the randomized phase 3 adjuvant trial of pembrolizumab versus placebo for stage III melanoma…
- Ep 75: Immune-mediated Myocarditis · 1 h 4 min · Season 2 Episode 75Summary In this (longest to-date) episode, James and Sapna delve into the not-so-rare occurence of immune-mediated myocarditis, particularly in the context of immune checkpoint…
- Ep 74: Best of ESMO 2025: Part 2 of 2 · 39 min · Season 2 Episode 74Summary In this Part 2 Best of ESMO 2025 episode of Melanoma Matters, hosts James Larkin and Sapna Patel cover the IO Biotech phase 3 trial, Checkmate 238 final results, the Safe…
