QCast: Data-Driven Dialogue in Drug Development
Quanticate
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Episode 70: Clinical Trial Planning and Design
Episode 70: Clinical Trial Planning and Design
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QCast by Quanticate is the podcast for biotech, pharma, and life science leaders looking to deepen their understanding of biometrics and modern drug development. Join co-hosts Tom and Jullia as they explore methodologies, case studies, regulatory shifts, and industry trends shaping the future of clinical research. Where biometric expertise meets data-driven dialogue, QCast delivers practical insights and thought leadership to inform your next breakthrough.
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70 bölümden en yeni 20 bölüm
- Episode 70: Clinical Trial Planning and Design · 11 dk · Bölüm 70Clinical trial design decisions can have consequences across the protocol, analysis and delivery of a study. In this QCast episode, co-hosts Jullia and Tom examine how a clear…
- Episode 69: SDTM Mapping Automation Tool · 11 dk · Bölüm 69In this QCast episode, co-hosts Jullia and Tom examine how SDTM mapping automation tools use approved rules and metadata to generate mapping specifications and SAS code, and…
- Episode 68: AI in Clinical Trial Design · 11 dk · Bölüm 68AI and machine learning can help research teams make more informed clinical trial design decisions, from assessing protocol feasibility to identifying suitable patient…
- Episode 67: The Analysis of Direct and Indirect Pathways in Observational Studies · 12 dk · Bölüm 67In this episode, Jullia and Tom discuss direct and indirect pathways in observational studies, with a focus on mediation analysis and what it can, and cannot, show. Using an…
- Episode 66: What is Clinical Traceability? · 12 dk · Bölüm 66Clinical traceability is about being able to follow evidence from a reported result back to its source and understand the transformations, decisions, and records in between. In…
- Episode 65: Clinical Trial Trends Shaping Modern Drug Development · 12 dk · Bölüm 65Clinical trial trends matter most when they affect how studies are designed, delivered, and overseen. In this QCast episode, co-hosts Jullia and Tom discuss how decentralised…
- Episode 64: Tipping Point Analysis in Clinical Trials · 10 dk · Bölüm 64Tipping point analysis helps trial teams understand how strongly a study conclusion depends on assumptions about missing data. In this QCast episode, co-hosts Jullia and Tom…
- Episode 63: Audit Trail Review in Clinical Trials · 10 dk · Bölüm 63Audit trail review can involve far more than checking whether a system records changes. In this QCast episode, co-hosts Jullia and Tom discuss how trial teams can decide what…
- Episode 62: Drug Adherence and Persistence · 11 dk · Bölüm 62Drug adherence and persistence measures built from claims or EHR databases depend as much on study definitions as recorded treatment events. In this QCast episode, co-hosts…
- Episode 61: The Role of Data Monitoring Committees (DMC) in Clinical Trials · 12 dk · Bölüm 61In this QCast episode, Jullia and Tom discuss the role of data monitoring committees, or DMCs, in clinical trials. They explain how DMCs support participant safety and trial…
- Episode 60: Oncology Phase 1 Trial Design · 11 dk · Bölüm 60In this QCast episode, Jullia and Tom discuss how oncology Phase 1 trial design has moved beyond simply identifying the maximum tolerated dose. They look at dose optimisation…
- Episode 59: Clinical Data Quality · 11 dk · Bölüm 59In this QCast episode, Jullia and Tom look at how clinical data quality is shaped from study set-up through collection, review and integration. They discuss why clear…
- Episode 58: Rescue Studies · 10 dk · Bölüm 58In this QCast episode, Jullia and Tom discuss how sponsors can assess a study in difficulty, decide how to handle existing databases and data, manage handovers, and set realistic…
- Episode 57: Clinical Trial Performance Metrics · 9 dk · Bölüm 57In this QCast episode, Jullia and Tom examine how clinical trial performance metrics can support better oversight without creating unnecessary reporting burden. They explain the…
- Episode 56: Bayesian Clinical Trial Design · 10 dk · Bölüm 56In this QCast episode, co-hosts Jullia and Tom explain how priors, posterior probabilities and predictive probabilities support clinical decisions. They also discuss external…
- Episode 55: What is Adaptive Trial Design? · 10 dk · Bölüm 55In this QCast episode, Jullia and Tom examine how adaptive trial design allows pre-specified changes to a clinical trial using accumulating interim data. They look at common…
- Episode 54: SAS vs R vs Python in Clinical Trials · 12 dk · Bölüm 54In this QCast episode, Jullia and Tom look at SAS vs R vs Python through the lens of clinical trial delivery. Rather than treating the choice as a programming preference, they…
- Episode 53: Decentralised Clinical Trials · 11 dk · Bölüm 53In this QCast episode, Jullia and Tom discuss decentralised clinical trials and what they mean for clinical development teams in practice. The episode looks at decentralisation…
- Episode 52: The Global Statistical Test for Multiple Endpoint Analysis · 10 dk · Bölüm 52In this QCast episode, Jullia and Tom discuss the Global Statistical Test for multiple endpoints analysis and why it can be useful when a clinical trial needs to assess more than…
- Episode 51: CDASH Standards and Conformance in Clinical Data Management · 10 dk · Bölüm 51In this QCast episode, Jullia and Tom discuss CDASH standards and conformance in clinical data management, with a focus on where CDASH sits in the clinical data flow and why it…
